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Table 1 IC50 values of the extract and fractions on AR inhibition

From: Plant-derived molecules from Saussurea grandifolia as inhibitors of aldose reductase

Sample Concentration
(μg/mL)
Inhibitiona (%) IC b50 (μg/mL)
MeOH extract 5 85.19 0.84
1 56.64
0.5 37.16
n-Hexane fraction 10 21.58
MC fraction 10 46.48
EtOAc fraction 1 93.41 0.12
0.1 57.21
0.05 24.37
n-BuOH fraction 10 84.07 3.33
5 67.28
1 8.67
TMGc 5 78.48 0.96
1 58.96
0.5 32.16
  1. aInhibition rate was calculated as a percentage with respect to the control value
  2. bIC50 value was calculated from least-squares regression analysis of the plot of the logarithm of three graded concentrations versus % inhibition
  3. cTMG was used as a positive control