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Fig. 5 | Applied Biological Chemistry

Fig. 5

From: Geraniin ameliorate experimental acute reflux esophagitis via NF-κB regulated anti-inflammatory activities in rats

Fig. 5

Inhibitory effects of geraniin on inflammatory protein and cytokine expression in esophagus. Expression of pro-inflammatory protein TNF-α, IL-1β, COX-2, p-IkB-α and p-p65. Rats were pre-treated with geraniin 15 and 30 mg/kg, and ranitidine 30 mg/kg body weight excluding normal and RE control for 90 min before surgery. After 5 h, the esophageal mucosa was cut, and then, the was abdomen open and removed from each rat. Data are mean ± standard deviation (SD). Significance: ##p < 0.01 and #p < 0.05 compared with normal control group; **p < 0.01 and *p < 0.05 compared with RE control group

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