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Applied Biological Chemistry
Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Anti-inflammatory and antioxidant effects of 2, 7-dihydroxy-4, 6-dimethoxy phenanthrene isolated from Dioscorea batatas Decne

Fig. 4

Effects of Nrf2/HO-1 signaling pathway on DDP-mediated anti-inflammatory activities. Raw 264.7 cells were cultured with 5 μg/mL of DDP with LPS in the absence or presence of SnPP (20 μM) of Brusatol (50 nM), each culture medium was collected. The levels of extracellular NO (a) and IL-1β (b) were analyzed. Intracellular protein expression levels of iNOS, COX-2 in LPS-activated Raw 264.7 cells were quantitatively analyzed (c). Bars (values) not sharing common letter indicate statistically significant difference from each other (p < 0.05)

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