Skip to main content
Applied Biological Chemistry
Fig. 3 | Applied Biological Chemistry

Fig. 3

From: Antimelanogenic activities of piperlongumine derived from Piper longum on murine B16F10 melanoma cells in vitro and zebrafish embryos in vivo: its molecular mode of depigmenting action

Fig. 3

Inhibitory effects of piperlongumine on four genes involved in melanin biosynthesis in a murine B16F10 cell line using RT-qPCR. α-MSH, α-melanocyte stimulating hormone; PL, piperlongumine; Mitf, microphthalmia associated transcription factor; Tyr, tyrosinase; Trp-1, tyrosinase-related protein 1; and Trp-2, tyrosinase-related protein 2. Significant differences are expressed by the symbols *, **, ***, and **** for expressing p < 0.05, p < 0.01, p < 0.001, and p < 0.0001, respectively. Significant differences in the comparison to α-MSH-treated cells are expressed by the symbols #, ##, ###, and #### as p < 0.05, p < 0.01, p < 0.001, and p < 0.0001, respectively

Back to article page