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Fig. 1 | Applied Biological Chemistry

Fig. 1

From: Methyl lucidone exhibits neuroprotective effects on glutamate-induced oxidative stress in HT-22 cells via Nrf-2/HO-1 signaling

Fig. 1

MLC protects HT-22 neurons against glutamate-induced neuronal cell death. a HT-22 cells were treated for 1 h with various concentrations of MLC to observe its own cytotoxicity. After washing out, the cells were incubated for 12 h in fresh media without MLC. All measurements of cell viability in this study were examined using MTT assay. **p < 0.01, compared to cells not treated with MLC (0 μM). b After pretreating with MLC for 1 h, the cells were washed and further incubated with glutamate (5 mM) for 12 h. **p < 0.01, compared to the group pretreated with MLC alone. The data indicate mean ± SEM (n = 3)

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