Fig. 3
From: Sex differences in glucose metabolism of streptozotocin-induced diabetes inbred mice (C57BL/6J)
The α- and β-cell masses in the pancreatic islets of the streptozotocin (STZ)-induced diabetes mice at 6 weeks after STZ treatment. a Immunostaining with insulin (red) and glucagon (green) antibodies. b β-cell mass. c α-cell mass. d Glucagon/insulin ratio. The glucagon/insulin ratio in the STZ-induced male group was significantly different from that of the STZ-induced female group, demonstrating that STZ is more toxic in the pancreatic islets of male mice compared to those in female mice