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Fig. 3 | Applied Biological Chemistry

Fig. 3

From: A trienone analog of curcumin, 1,7-bis(3-hydroxyphenyl)-1,4,6-heptatrien-3-one, possesses ROS- and caspase-mediated apoptosis in human oral squamous cell carcinoma cells in vitro

Fig. 3

The effects of trienone 11 on the induction of apoptosis in CLS-354/DX and CLS-354/WT cells. CLS-354/DX cells (a, b) and CLS-354/WT (c, d) were treated with trienone 11 at 15–30 μM and 15 μM, respectively, for 24 h. Apoptosis was determined by flow cytometric analysis using double staining with Annexin V-FITC and propidium iodide, and the results are represented as scatter plots (a, c) and as percentages of apoptotic cells (b, d). Values are expressed as mean ± standard deviation (SD) of duplicate samples in three independent experiments. Different letters above the bar indicate the significant difference (p < 0.05)

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