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Table 2 Significantly altered metabolites of zebrafish exposed to lindane in targeted metabolomics (VIP > 1.0, SE < 1.0, and p-value < 0.05)

From: Toxicometabolomics of lindane in adult zebrafish (Danio rerio) using GC-MS/MS and LC-Orbitrap-MS/MS

No. Compound name VIP Standard error P value No. Compound name VIP Standard error P value No. Compound name VIP Standard error P value
1 Hypoxanthine 1.35 0.49 1.41E−06 16 3-Aminoglutaric acid 1.19 0.39 3.69E−04 31 Ribulose 5-phosphate 1.23 0.62 5.52E−03
2 2-Aminoethanol 1.38 0.55 1.44E−06 17 Palmitic acid 1.31 0.29 4.73E−04 32 Docosahexaenoic acid 1.03 0.59 6.42E−03
3 Lysine 1.31 0.28 7.29E−06 18 Proline 1.16 0.39 5.91E−04 33 Arachidonic acid 1.01 0.58 7.45E−03
4 Tyramine 1.31 0.28 9.58E−06 19 Leucine 1.15 0.39 6.81E−04 34 Eicosapentaenoic acid 1.00 0.57 7.52E−03
5 Xanthine 1.26 0.46 2.69E−05 20 Methionine 1.13 0.39 9.15E−04 35 6−Phosphogluconic acid 1.00 0.48 7.90E−03
6 Gluconic acid 1.32 0.29 3.69E−05 21 Monostearin 1.16 0.44 9.40E−04 36 Palmitoleic acid 1.00 0.60 8.30E−03
7 Mannose 6-phosphate 1.28 0.29 3.92E−05 22 Tyrosine 1.10 0.45 1.71E−03 37 Myristic acid 1.02 0.51 8.62E−03
8 Glucose 1.28 0.36 5.09E−05 23 Ribose 1.11 0.71 2.25E−03 38 Heptadecanoic acid 1.44 0.57 9.43E−03
9 Glucose 6-phosphate 1.26 0.31 7.23E−05 24 Oleic acid 1.09 0.52 2.62E−03 39 Ribose 5−phosphate 1.28 0.77 1.55E−02
10 gluconic acid lactone 1.26 0.39 1.01E−04 25 Elaidic acid 1.08 0.53 2.70E−03 40 Stearic acid 1.32 0.57 2.18E−02
11 Valine 1.23 0.26 1.19E−04 26 Glyceric acid 1.15 0.53 2.73E−03 41 Glutamic acid 1.41 0.96 2.51E−02
12 Sedoheptulose 7-phosphate 1.22 0.51 1.40E−04 27 Creatinine 1.21 0.64 2.95E−03 42 Methyl serine 1.51 0.78 2.55E−02
13 Isoleucine 1.19 0.39 2.84E−04 28 Tryptophan 1.05 0.58 3.00E−03 43 Threonine 1.00 0.64 2.58E−02
14 Aspartic acid 1.21 0.39 3.31E−04 29 Alanine 1.07 0.43 4.40E−03 44 Caproic acid 1.58 0.66 2.94E−02
15 Phenylalanine 1.18 0.36 3.51E−04 30 Uracil 1.05 0.49 5.34E−03 45 Histidine 1.13 0.52 3.12E−02