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Table 3 Significantly altered metabolites of zebrafish exposed to lindane in non-targeted metabolomics (VIP > 1.0, SE < 1.0, and p-value < 0.05)

From: Toxicometabolomics of lindane in adult zebrafish (Danio rerio) using GC-MS/MS and LC-Orbitrap-MS/MS

No Metabolite Molecular formula Adduct Molecular weight RT (min) mzCloud matching score (%) HMDB VIP Standard error p-value
1 5(S),15(S)-DiHETE C20H32O4 [M−H] 336.23 20.60 95.30 HMDB0010216 1.95 0.78 8.0E−05
2 Lipoxin B4 C20H32O5 [M−H] 352.22 19.92 84.00 HMDB0005082 1.94 0.47 1.1E−04
3 2-(14,15-Epoxyeicosatrienoyl) glycerol C23H38O5 [M + H]+ 376.26 22.13 85.60 HMDB0013651 1.66 0.76 4.1E−03
4 Drospirenone C24H30O3 [M + H]+ 366.21 21.76 89.30 HMDB0015467 1.51 0.59 1.5E−02
5 Choline C5H14NO [M + H]+ 103.10 1.28 97.30 HMDB0000097 1.49 0.31 1.8E−02
6 Adrenic acid C22H36O2 [M + H]+ 332.27 23.59 94.10 HMDB0002226 1.44 0.78 2.3E−02
7 N6,N6,N6-Trimethyl-L-lysine C9H20N2O2 [M + H]+ 188.1 1.20 86.00 HMDB0001325 1.36 0.76 3.0E−02