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Fig. 3 | Applied Biological Chemistry

Fig. 3

From: Propofol suppresses non-small cell lung cancer progression by modulating circ_0001727/miR-516b-5p/LRRC1 axis

Fig. 3

Propofol limited NSCLC cell malignant behaviors by regulating circ_0001727. A Circ_0001727 level was examined in NSCLC cells transfected with si-NC or si-circ_0001727. BI NSCLC cells were divided into 4 groups: control group, propofol group, propofol + si-NC group, and propofol + si-circ_0001727 group. B CCK-8 analysis was applied for detecting cell viability. C Cell colony-forming ability was evaluated by colony formation assay. Cell migration (D) invasion (E) were evaluated using transwell assay (× 100). F Angiogenesis was determined by tube formation assay. G Cell apoptosis was detected via flow cytometry. H, I WB was used to measure the protein expression of VEGFA and Bcl-2. *P < 0.05.

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