Fig. 4
From: Artocarpesin acts on human platelet aggregation through inhibition of cyclic nucleotides and MAPKs
Effects of artocarpesin on TXA2 generation, cPLA2, p38phosphorylation and cyclic nucleotides. A Effects of artocarpesin on collagen-induced TXA2 generation. B Effect of artocarpesin on collagen-induced cPLA2 phosphorylation. C Effect of artocarpesin on collagen-induced p38 phosphorylation. D Effect of artocarpesin on collagen-induced cAMP production. E Effect of artocarpesin on collagen-induced cGMP production. Measurement of TXA2 generation, Western blot and cyclic nucleotides level was performed as described in “Materials and Methods” section. The data are expressed as the mean ± standard deviation (n = 4). *p < 0.05, **p < 0.01 versus the collagen-stimulated human platelets