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Applied Biological Chemistry
Fig. 1 | Applied Biological Chemistry

Fig. 1

From: Orlistat, a competitive lipase inhibitor used as an antiobesity remedy, enhances inflammatory reactions in the intestine

Fig. 1

Intestinal epithelial mRNA expression of A TNF-α, B IL-6, C occludins and D Mucin-2 analyzed by qRT-PCR for the three treatment groups; Normal diet-fed control group, High fat diet-fed (HFD) and HFD-fed with Orlistat (HFDOrl) treatment groups. E Effect of extracts from 100 mg of fecal matter from mice in the Orlistat treatment (HFDOrl) group and pure Orlistat on ROS production based on the MitoSOX superoxide indicator in Caco-2 cells counter-stained with DAPI (F) Mean optical density of randomly selected fields of the representative images. Untreated and DMSO-treated cells were used as controls. Real-time PCR results for data are presented as the mean concentration ± SEM. Different letters denote the significance of the differences compared with the control (p < 0.05)

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