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Applied Biological Chemistry
Fig. 2 | Applied Biological Chemistry

Fig. 2

From: Depressing hsa_circ_0058092 functions an integrated anti-proliferation and anti-motility role in gastric cancer partially through targeting miR-1294/SIX1 axis

Fig. 2

Effects of hsa_circ_0058092 knockdown on cell proliferation and motility of GC cells in vitro. AGS and HGC-27 cells were transfected with si-hsa_circ_0058092 (#1, #2 or #3) or si-NC. A, B qPCR detected relative expression of hsa_circ_0058092. C Colony formation assay determined the number of colonies formed in 2 weeks. D EdU assay measured EdU positive cell rate (%) in Hoechst positive cells. E Scratch wound assay displayed relative wound closure (%) after 24 h. F, G Transwell assays tested migration rate (%) and invasion rate (%) after 24 h. H, I Western blotting detected relative protein expression of E-cadherin and N-cadherin with correction to GAPDH. **P < 0.01 and ***P < 0.001

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