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Applied Biological Chemistry
Fig. 7 | Applied Biological Chemistry

Fig. 7

From: Depressing hsa_circ_0058092 functions an integrated anti-proliferation and anti-motility role in gastric cancer partially through targeting miR-1294/SIX1 axis

Fig. 7

Role of blocking hsa_circ_0058092 in tumorigenicity of GC cells in vivo. AGS cells stably expressing sh-hsa_circ_0058092 or sh-NC were used to induce xenograft tumors in nude mice (n = 6). A Xenograft tumors were excised and photographed, and the most representative tumors were presented. B Tumor volume was monitored at an interval of every 5 days after cell injection. C Tumor weight was determined after photographing. D–F qPCR detected relative expression of hsa_circ_0058092, miR-1294 and SIX1 mRNA, and G, J western blotting measured relative protein expression of SIX1, E-cadherin and N-cadherin, and H, I IHC examined in situ expression of SIX1 and ki-67 in xenograft tumor tissues

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