Fig. 2

Knockdown of circTRRAP reduced PCa cell malignancy and glycolysis. A Transfection efficiencies of three siRNAs targeting circTRRAP were determined by qRT-PCR. B–E Cell viability, proliferation, migration, and invasion in si-circTRRAP#1 or si-NC-transfected PCa cells were estimated by MTT, EdU, and transwell assays. F and G PCNA, MMP2, and MMP9 protein levels in si-circTRRAP#1 or si-NC-transfected PCa cells were detected by western blot. G and H The glucose uptake and lactate production of si-circTRRAP#1 or si-NC-transfected PCa cells were measured. *P < 0.05