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Fig. 3 | Applied Biological Chemistry

Fig. 3

From: circTUBGCP5 promotes liver cancer progression and glycolysis by up-regulating the expression of ACSL4

Fig. 3

CircTUBGCP5 may act as a sponge for miR-144-3p. A MiR-1278, miR-145-5p, and miR-144-3p were identified to possibly interact with circTUBGCP5 through the intersection of circintractome, starbase, and circbank databases. B and C The interaction of circTUBGCP5 and miR-144-3p was identified by RNA-pull down assay. D The schematic drawing showed the sequence of wild-type (wt) and mutant (mut) circTUBGCP5. E Overexpression efficiency of miR-144-3p using qRT–PCR. F and G The luciferase activity of circTUBGCP5-wt and circTUBGCP5-mut in Huh-7 and HCCLM3 cells after cotransfection with miR-144-3p. H The miR-144-3p level in LCa (n = 46) and normal (n = 46) tissues by qRT–PCR. I The circTUBGCP5 level in LCa cells (Huh-7 and HCCLM3) and normal cell (THLE-2) using qRT–PCR. Data were presented as mean ± SD. **P < 0.01, ***P < 0.001

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