Fig. 4

Circ_0026359 was associated with miR-140-3p. A The schematic diagram showing the binding sites of circ_0026359 for miR-140-3p. B and C Dual-luciferase reporter assay was implemented to identify the targeting relationship between circ_0026359 and miR-140-3p. D and E MiR-140-3p expression was checked by qRT-PCR in GC tissues (N = 30), healthy gastric tissues (N = 30) and GES1, AGS and HGC-27 cells. F Spearman correlation analysis was employed to reveal the correlation between miR-140-3p and circ_0026359 expression in GC tissues. *P < 0.05