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Applied Biological Chemistry
Fig. 1 | Applied Biological Chemistry

Fig. 1

From: Circ_0000554 is identified as a cancer-promoting circRNA in colorectal cancer by regulating the miR-1205/LASP1 axis

Fig. 1

Circ_0000554 was upregulated in CRC tissues and cells. A The histopathologic staining of Ki67 was detected by IHC assay. B The data of circRNA expression in CRC tissues were collected from a circRNA expression profile (GEO accession: GSE126094). C QRT-PCR was exploited to determine the expression of circ_0000554 in CRC tissues and normal tissues. D Overall survival was analyzed by Kaplan–Meier plot and log-rank test. E The expression of circ_0000554 in different TNM stages (I–II and III) of CRC patients was determined by using qRT-PCR. F QRT-PCR was used to detect the expression of circ_0000554 in CRC patients with (Yes) and without (No) lymph node metastasis. G The expression level of circ_0000554 was assessed by qRT-PCR assay in CRC cells and NCM460 cells. (H–I) QRT-PCR analysis of circ_0000554 expression in SW480 and HCT-116 cells treated with or without RNase R. ***P < 0.001, ****P < 0.0001

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