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Applied Biological Chemistry
Fig. 2 | Applied Biological Chemistry

Fig. 2

From: Circ_0000554 is identified as a cancer-promoting circRNA in colorectal cancer by regulating the miR-1205/LASP1 axis

Fig. 2

Circ_0000554 knockdown inhibited CRC malignant progression. SW480 and HCT-116 cells were transfected with si-NC or si-circ_0000554. A Circ_0000554 expression was detected by qRT-PCR. B Cell viability was detected by CCK8 assay. C Cell proliferation was studied by EdU assays. D Cell apoptosis was investigated by flow cytometry analysis. E–F Transwell assay and wound-healing assay were performed to detect the invasion (F) and migration (G) capabilities. G and H The protein expression of C-myc and MMP2 was checked by western blot analysis. ***P < 0.001, ****P < 0.0001

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