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Fig. 3 | Applied Biological Chemistry

Fig. 3

From: Circ_0000554 is identified as a cancer-promoting circRNA in colorectal cancer by regulating the miR-1205/LASP1 axis

Fig. 3

MiR-1205 was a target of circ_0000554 in CRC cells. A The potential binding sites between circ_0000554 and miR-1205. B QRT-PCR analysis of miR-1205 expression in SW480 and HCT-116 cells transfected with miR-1205 mimic or miR-NC. C–D Dual-luciferase reporter assay was performed to confirm the relationship between circ_0000554 and miR-1205. E–F RIP was performed using Ago2 antibody in CRC cells, then the enrichment of miR-1205 and circ_0000554 was detected. G QRT-PCR analysis of miR-1205 level in CRC tissues and adjacent normal tissues. H The correlation between circ_0000554 and miR-1205 expression was analyzed by Pearson analysis. I QRT-PCR analysis of miR-1205 level in CRC cells and NCM460 cells. ***P < 0.001, ****P < 0.0001

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