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Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Circ_0000554 is identified as a cancer-promoting circRNA in colorectal cancer by regulating the miR-1205/LASP1 axis

Fig. 4

MiR-1205 was involved in circ_0000554-mediated regulation in CRC cell progression in vitro. SW480 and HCT-116 cells were transfected with si-NC, si-circ_0000554, si-circ_0000554 + anti-miR-NC or si-circ_00005541 + anti-miR-1205. A MiR-1205 expression was determined by qRT-PCR. B Cell viability was detected by MTT assay. C The EdU assays were used to measure proliferation capability of SW480 and HCT-116 cells. D The apoptotic cells were monitored by flow cytometry assay. EF Cell invaded and migrated abilities were assessed through transwell assay and wound-healing assay, respectively. GH The protein levels of C-myc and MMP2 were performed by western blot. **P < 0.01, ***P < 0.001, ****P < 0.0001

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