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Applied Biological Chemistry
Fig. 6 | Applied Biological Chemistry

Fig. 6

From: Circ_0000554 is identified as a cancer-promoting circRNA in colorectal cancer by regulating the miR-1205/LASP1 axis

Fig. 6

LASP1 overexpression recovered CRC cell malignant behaviors suppressed by miR-1205 restoration. SW480 and HCT-116 cells were transfected with miR-NC, miR-1205, miR-1205 + pcDNA, or miR-1205 + LASP1. A The protein expression level of LASP1 was shown by western blot assay. B, C The proliferation ability was determined by MTT and EdU assays. D The apoptosis rate of CRC cells was shown by flow cytometry assay. E–F The invasion and migration were determined by transwell assay and wound-healing assay, respectively. G–H The protein levels of C-myc and MMP2 were measured by western blot. **P < 0.01, ***P < 0.001, ****P < 0.0001

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