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Applied Biological Chemistry
Fig. 8 | Applied Biological Chemistry

Fig. 8

From: Circ_0000554 is identified as a cancer-promoting circRNA in colorectal cancer by regulating the miR-1205/LASP1 axis

Fig. 8

Knockdown of circ_0000554 reduced tumor growth of CRC in vivo. A The expression of circ_0000554 was determined by QRT-qPCR assay in HCT-116 cells stably transfected with sh-NC or sh-circ_0000554. B–C The effects of circ_0000554 silencing on the volume and weight of the neoplasms were revealed. D–F The expression of circ_0000554, miR-1205 and LASP1 were determined by qRT-PCR or western blot analysis. G The effects of circ_0000554 knockdown on LASP1, C-myc and MMP2 expression in sh-circ_0025033 and sh-NC groups were investigated by IHC assay. **P < 0.01 and ***P < 0.001

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