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Fig. 2 | Applied Biological Chemistry

Fig. 2

From: Regulatory effect of peroxiredoxin 1 (PRDX1) on doxorubicin-induced apoptosis in triple negative breast cancer cells

Fig. 2

The anticancer effect of doxorubicin (DOX) on MDA-MB-231 cells. A A 3-(4,5-dimethyldiazol)-2-yl-2,5-diphenyltetrazolium bromide (MTT) assay was used to detect cell survival rate. B MDA-MB-231 cells were treated with DOX at concentrations of 2 μM and 5 μM, and apoptosis was detected by immunofluorescence detection of Annexin V-PE. C Western blot analysis was used to detect the expression of mitochondrial-dependent apoptosis protein. D The protein expression of peroxiredoxins (PRDXs) was detected by western blot analysis. E The expression levels of PRDX1, PRDX2, PRDX3, PRDX4, PRDX5, and PRDX6 proteins were statistically analyzed

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