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Applied Biological Chemistry
Fig. 8 | Applied Biological Chemistry

Fig. 8

From: Regulatory effect of peroxiredoxin 1 (PRDX1) on doxorubicin-induced apoptosis in triple negative breast cancer cells

Fig. 8

Peroxiredoxin 1 (PRDX1) regulates doxorubicin (DOX)-induced apoptosis of MDA-MB-231 cells through phosphoinositide 3-kinase (PI3K)/protein kinase B (Akt)/glycogen synthase kinase 3β (GSK3β) signaling. A Western blot was used to detect the expression of PI3K, Akt, and P-Akt proteins. B The expression levels of PI3K and P-Akt-related proteins were statistically analyzed. C Apoptosis was observed by fluorescence microscopy. D The expression levels of P-Akt, Akt, Bad, Bcl-2, C-Cas9, C-Cas7, C-Cas3, and C-Cas3 were detected by western blot analysis. E The expression levels of P-Akt, bad, Bcl-2, C-Cas9, C-Cas7, and C-Cas3-related proteins were statistically analyzed

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