Table 3 Effect of the synthesized chemical compound 3 and its coated form on the levels of AST, ALT, ALP and GGT in DEN-induced HCC in rats and therapeutic groups

AST(U/l)

% of change

% of improvement

75.00 ± 3.90^a

–

–

259.0 ± 6.88^b

 + 245.33

–

158.60 ± 4.20^c

 + 111.47

133.87

120.90 ± 3.00^d

 + 101.20

184.13

130.00 ± 5.10^d

 + 73.33

172.00

ALT (U/l)

% of change

% of improvement

49.02 ± 3.10^e

–

–

129.00 ± 4.00^a

 + 163.160

–

79.00 ± 3.23^d

 + 61.20

102.04

65.40 ± 2.50 ^g

 + 33.42

129.74

63.00 ± 3. 80 ^g

 + 28.52

134.64

ALP(U/l)

% of change

% of improvement

42.19 ± 3.90 ^h

–

–

257.67 ± 9.60^b

 + 510.74

–

95.00 ± 5.00^f

 + 125.18

385.57

67.00 ± 3.78 ^k

 + 58.81

451.93

80.40 ± 2.0ⁿ

 + 90.57

420.17

GGT (U/L)

% of change

% of improvement

10.23 ± 0.23^a

–

–

40.22 ± 3.90^b

 + 293.16

–

22.60 ± 2.11^c

 + 120.92

172.24

17.78 ± 1.20^d

 + 73.80

219.35

25.70 ± 3.90^e

 + 151.22

141.94