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Fig. 6 | Applied Biological Chemistry

Fig. 6

From: Gryllus bimaculatus extract protects against palmitate-induced β-cell death by inhibiting ceramide synthesis

Fig. 6

GB extract decreases PAL-induced β-cell death. MIN6 cells were treated with 200 µg/ml GB extract for 24 h, followed by 0.5 mM PAL for another 24 h. A Representative western blots of indicated proteins after PAL treatment in GB extract-pretreated MIN6 cells. B Nitrite and C TNF-α levels were measured after PAL treatment in GB extract-pretreated MIN6 cells (n = 3). Values are expressed as mean ± SEM compared to control group; *P < 0.05, ***P < 0.001 and compared to PAL-treated group; ##P < 0.01. All experiments were performed in triplicate. GB Gryllus bimaculatus, PAL palmitate, TNF-α tumor necrosis factor-alpha, Bcl2 B-cell lymphoma 2, eIF2α eukaryotic translation initiation factor 2A, iNOS inducible nitric oxygen synthase, PERK protein kinase R-like endoplasmic reticulum kinase, Con control (untreated)

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