Fig. 1

a Effects of IE on the ROS production in CORT-treated HT22 cells. DCFH-DA fluorescence images and intensity. HT22 cells were co-treated with CORT (200 μM) and IE (10 or 100 μg/mL) for 24 h. After staining using DCFH-DA (5 μM) for 45 min, fluorescence images were captured. b-c Effects of IE on the MAO enzyme activity and protein expression. b IE inhibited both MAO-A and MAO-B activity at concentrations of 1–100 μg/mL. c Immunoblot showing MAO protein expression. Data are presented as mean ± standard deviation. #p < 0.05, ##p < 0.01, ###p < 0.001 vs. CTL; *p < 0.05, **p < 0.01 vs. CORT-only treated cells