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Applied Biological Chemistry
Fig. 5 | Applied Biological Chemistry

Fig. 5

From: Baicalein facilitates gastric cancer cell apoptosis by triggering endoplasmic reticulum stress via repression of the PI3K/AKT pathway

Fig. 5

Baicalein triggered ERS to induce apoptosis by inhibiting the PI3K/AKT pathway via the activation of BTG3. A PI3K, p-PI3K, AKT, and p-AKT proteins determined by Western blot; B Expressions levels of Grp78, and CHOP determined by Western blot; C Intracellular Ca2 + levels measured using Fluo-3 AM fluorescent probes; D Intercellular Ca2 + levels measured using flow cytometry; E Apoptosis detected by flow cytometry. Cell experiment was duplicated thrice, and the data were expressed as mean ± SD. One-way ANOVA was used for comparisons among multiple groups, followed by Tukey’s test. *p < 0.05, **p<0.01, ***p < 0.001

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