Fig. 3
From: Anti-inflammatory effect of taxifolin in TNF-α/IL-17A/IFN-γ induced HaCaT human keratinocytes
Taxifolin suppresses psoriasis-related cytokines and chemokines in HaCaT cells treated with TNF-α + IL-17A + IFN-γ. A Taxifolin at concentrations up to 300 μg/mL is not cytotoxic to TNF-α + IL-17A + IFN-γ treated HaCaT cells. B IL-1α, C IL-1β, D IL-6, E CXCL, (F) CCL20 mRNA expression levels determined by real-time RT-PCR. Brazilin was used as positive control. #, p < 0.05; ##, p < 0.01; and ###, p < 0.001 versus control; *, p < 0.05, **, p < 0.01, ***, p < 0.001 versus TNF-α + IL-17A + IFN-γ treated HaCaT cells