Fig. 8

The characterization of AuNS@4-MBA@Au and AuNS@4-MBA@Au@DNA (thiolated ssDNA conjugates). Raman spectra (A) and histogram of SERS signals at wavenumber of 1075 cm-1 (B) for AuNSs, 4-MBA, physically mixed solution of AuNSs together with 4-MBA and AuNS@4-MBA@Au. C UV–Vis absorbance spectrum of each sample. D DLS profile of each sample. E Picture of each sample. 1: AuNPs; 2: AuNSs; 3: AuNS@4-MBA; 4: AuNS@4-MBA@Au; 5: AuNS@4-MBA@Au@DNA. TEM images of AuNPs (F), AuNSs (G), AuNSs@4-MBA (H), AuNS@4-MBA@Au (I) and the crosslinked AuNS@4-MBA@Au@DNA (J) (Figure from Zhuang et al., Biosensors and Bioelectronics 207 (2022) 114167, Copyright by Elsevier; used with permission)