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Applied Biological Chemistry
Fig. 2 | Applied Biological Chemistry

Fig. 2

From: Knockdown of circ_0006872 alleviates CSE-induced human bronchial epithelial cells injury in chronic obstructive pulmonary disease

Fig. 2

Knockdown of circ_0006872 attenuates CSE-induced 16HBEC injury. A The expression level of circ_0006872 was detected using qRT-PCR in non-smokers (n = 35), smokers (n = 35), and smokers with COPD (n = 35). B Levels of circ_0006872 in 16HBECs exposed to different concentrations of CSE. C Stability analysis by RNase R treatment. D–J 16HBECs were transfected with si-circ_0006872 or si-NC and then exposed with 2% CSE for 24 h. D Transfection efficiency. E, F 16HBEC proliferation analysis. G 16HBEC apoptosis detection. H Levels of Bax and Bcl-2 in 16HBECs. I Levels of IL-6 and TNF-α in 16HBECs. J Measurement of SOD content in 16HBECs using a commercial kit. **P < 0.01, ***P < 0.001, ****P < 0.0001

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