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Table 1 Top 20 up-regulated genes with HFD supplemented with Filbertone (HFD-Fil) compared to high-fat diet (HFD)

From: Filbertone, (2E)-5-methyl-2-hepten-4-one, regulates thermogenesis and lipid metabolism in skeletal muscle of a high-fat diet fed mice

Gene ID

Gene description

log2FC

Ucp1

Uncoupling protein 1 (mitochondrial, proton carrier)

5.631

Cidea

Cell death-inducing DNA fragmentation factor, alpha -like effector A

3.410

Hspa1a

Heat shock protein 1 A

2.487

Dkk3

Dickkopf WNT signaling pathway inhibitor 3

1.869

Tbx1

T-box 1

1.818

Banp

BTG3 associated nuclear protein

1.569

Lrtm2

Leucine-rich repeats and transmembrane domains 2

1.569

Pck1

Phosphoenolpyruvate carboxykinase 1, cytosolic

1.399

Prkcz

Protein kinase C, zeta

1.380

Ankrd2

Ankyrin repeat domain 2 (stretch responsive muscle)

1.368

Cbx8

Chromobox 8

1.361

Cfd

Complement factor D (adipsin)

1.290

Pitx3

Paired-like homeodomain transcription factor 3

1.283

Entpd4b

Ectonucleoside triphosphate diphosphohydrolase 4B

1.230

Katnal2

Katanin p60 subunit A-like 2

1.225

Acot1

Acyl-CoA thioesterase 1

1.222

Actc1

Actin, alpha, cardiac muscle 1

1.202

Gm5420

Predicted gene 5420

1.173

Ppara

Peroxisome proliferator activated receptor alpha

1.161

Snph

Syntaphilin

1.137