Fig. 2

The lack of immunotoxicity of Rosae extract; its effects on the cellularities of the secondary lymphoid organs. The mice were killed 15 h after the fifth challenge, and the mesenteric LNs (mLNs) and the spleens were taken from the respective group of mice. The numbers of cells in the mLNs (A) and the spleens (B) were examined. Normal BALB/C mice (neither immunized nor challenged) were left untreated or treated p.o. with either Dexamethasone (2.5 mg/kg) or Rosae extract (400 mg/kg) as indicated for 15 days, and the numbers of cells in the mLNs (C) and the spleens (D) from the respective group of mice were examined. Group description is shown as shown in Fig. 1A. Asterisk (*) denotes p < 0.05 by Student’s t test. The data represent mean ± SD of five mice per group