Oxidative metabolism of quinazoline insecticide fenazaquin by Aspergillus niger

Applied Biological Chemistry

Table 1 First- or pseudo-first-order kinetic parameters of fenazaquin degradation

Classification	Inhibitors	Oxidants (mg/L)	Rate (/day)	Half-lives (day)	R ^2,a
Chemical oxidation by MCPBA	–	20	0.06	0.5	0.9591
		60	0.11	0.3	0.9693
		200	0.26	0.1	0.9622
Biodegradation	Non-sterile	–	1.13	0.6	0.9912
	Sterile	–	ND^b	–	–
	Medium	–	ND	–	–
Biodegradation inhibitors^c	MTZ^d	–	0.44	1.6	0.9962
	PBO	–	0.01	58.7	0.9407
	KCZ	–	0.58	1.2	0.9107
	MCN	–	0.42	1.7	0.9415
	MCN^e	–	0.38	1.8	0.9696
	MCN^e	–	0.16	4.3	0.9815

^aRegression coefficient
^bNo degradation (ND)
^cInhibitor concentration (5 mg/L)
^dMTZ methimazole, PBO piperonyl butoxide, KCZ ketoconazole, MCN myclobutanil
^eConcentration of myclobutanil: 25 and 100 mg/L