Fig. 1

Changes in body weight, food intake, fasting blood glucose, and HbA1c. a–b Body weight and food intake were measured at 3, 6, 9, and 12 months. c–d Fasting blood glucose and HbA1c were measured at 3, 6, 9, and 12 months after 16 h fasting. These data are expressed as mean ± S.D. *p < 0.05 compared with same sex. ^#p < 0.05, ^##p < 0.01, ^###p < 0.005 compared between male and female