Fig. 2
From: Synthesis and anticancer activities of polymethylenedioxy analogues of combretastatin A-2
Predicted binding conformations of CA-4 (yellow), overlaid on surface area of crystallographic structures of CA-4 (green) and β-tubulin with description of binding pocket (a), and polymethylenedioxy compounds 4 (red) and 5 (blue) (b), 6 (yellow) and 7(pink) (c), 11 (brown) and 12 (pale blue) (d), and 13 (dark green) and 14 (violet) (e) on β-tubulin overlaid on crystallographic structure of CA-4 in 5LYJ (green)