Fig. 3
From: Anti-inflammation activity of brazilin in TNF-α induced human psoriasis dermatitis skin model
Brazilin down-regulated phosphorylation of MAPK (ERK, p38, JNK) and STAT3 proteins related to TNF-α signal transduction in HaCaT cells. The phosphorylated protein expression of ERK, p38, and JNK, STAT3 were decreased when brazilin concentration was increased (a, c, e, g). There were comparisons of ERK, JNK and p38, STAT3 phosphorylation by protein quantification using image J program (b, d, f, h). Data are presented as mean ± S.D. of triplicate determinations. ##p < 0.01, ###p < 0.001, compared to control, *p < 0.05, **p < 0.01, ***p < 0.001 compared to TNF-α group