Fig. 4
From: Anti-inflammation activity of brazilin in TNF-α induced human psoriasis dermatitis skin model
The TEER value was measured to verify the effect of brazilin on epithelial resistance in the presence of TNF-α. TNF-α induced inflammation caused the decrease of TEER value as time dependent manner. Also, DON used as a negative control showed same pattern with TNF-α. However, co-treatment with TNF-α (20 ng/mL) + Brazilin (7 μg/mL) significantly increased TEER of HaCaT cell as dose dependent manner. Results are presented as the mean ± S.D. of the percentage of control density (O.D) in triplicate