Fig. 3
From: Effects of dietary fibers and prebiotics in adiposity regulation via modulation of gut microbiota
Interaction between SCFAs, GPR43 and GPR41 receptors. (1) Bacteria in the gut interact with complex dietary carbohydrates produced by SCFAs through hydrolysis and fermentation; (2) The binding between SCFAs and GPR43 receptor in enterocytes promotes the release of GLP-1, increasing insulin sensitivity; (3) GPR43 activation via SCFAs interactions in the adipocyte suppresses insulin release, inhibiting fat stores in adipose tissue; (4) SCFAs-GPR41 receptor binding increases the release of PYY, reducing the development of obesity