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Applied Biological Chemistry
Fig. 5 | Applied Biological Chemistry

Fig. 5

From: PF4V1 affects the progression of oral squamous cell carcinoma by regulating Wnt/β-catenin pathway and angiogenesis

Fig. 5

PF4V1 affected the tumor formation of oral cancer cells in vivo. a The curves of tumor size were monitored every 5 days. b The curves of the weight of nude mice were monitored every 5 days. c Tumor weights were shown for overexpression and suppression expression of PF4V1 in SCC-9 and CAL-27 cells in the end of the study. *P < 0.05, ***P < 0.01, ***P < 0.001 versus the corresponding control group; d The tumors were separated from xenografts. e The HE staining results of tumor tissues and the pictures were enlarged 200 (mark 200 in the image) and 400 times (mark 400 in the image). PF4V1: PF4V1 overexpression group; Ctrl-PF4V1: the control vector of PF4V1 overexpression group; Ctrl-shRNA: the control vector of PF4V1 silence group; PF4V1-shRNA: PF4V1 silence group

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