Fig. 4
From: Bisphenol A disrupts inflammatory responses via Nod-like receptor protein 3 pathway in macrophages
Effect of BPA on ATP-primed NLRP3 inflammasome activation and the expression of IL-1β and IL-18 in RAW 264.7 macrophages. a Macrophages were treated with various concentrations of BPA (0.1–10 μg/mL) for 7 h and then treated with ATP for 1 h. b–d RAW 264.7 macrophages were treated with several concentrations of BPA for 23 h and incubated with ATP for 1 h. Whole cell lysates were investigated by western blot assay. e RAW 264.7 macrophages were transfected with siNLRP3 and treated with BPA for 23 h and then incubated with ATP for 1 h. Data are expressed as the mean ± S.E.M of three independent experiments. *p < 0.05, significantly different from the untreated group