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Applied Biological Chemistry
Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Irigenin exerts anticancer effects on human liver cancer cells via induction of mitochondrial apoptosis and cell cycle arrest

Fig. 4

a Flow cytometric analysis was carried out to determine the effects of irigenin on different phases of cell cycle in HepG2 and SNU-182 cells. Results showed it induced G2/M phase cell cycle arrest in both HepG2 as well as SNU-182 cells. b Western blotting assay showing the levels of expressions of cell cycle allied proteins in irigenin treated HepG2 and SNU-182 cells. Results revealed downregulation in the levels of expressions of cell cycle allied proteins (CDK1, Cyclin-B, Cyclin-A, Cyclin-D and Cyclin-E) in both the cell lines. The experiments were performed in triplicate

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