Fig. 6

Sulforaphane impeded mitochondrial biogenesis in the absence of p53. Both types of HCT116 cells were treated with sulforaphane (0, 1, or 10 μM) for 8 h. a The ratio of mitochondrial DNA (mtDNA) to nuclear DNA (nDNA) in the HCT116 cells was quantified using real-time qPCR. b PGC1α protein expression was examined using western blotting and densitometric analysis. Values represent mean ± SEM (N = 3). Statistical differences are indicated by different alphabetical letters for multiple comparisons