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Applied Biological Chemistry
Fig. 4 | Applied Biological Chemistry

Fig. 4

From: Potato extract inhibits lipase activity and ameliorates gut microbiome dysbiosis and weight gain in mice fed a high-fat diet

Fig. 4

Serum biochemical values are affected by PI treatment. a ND and PI treatment had significantly similar trends in glucose concentration over time during the intraperitoneal glucose tolerance test (IPGTT), while the orlistat-treated group maintained the lowest blood glucose concentration in comparison to those fed a HFD during the first 60 min (p = 0.001). Meanwhile, the HFD group had the highest blood glucose concentration through-out the test period (p < 0.05). b The ND, orlistat, and PI-treated groups all had significantly lower concentrations of blood glucose during the intraperitoneal insulin tolerance test (IPITT) as compared to the HFD group (p < 0.05). The area under the curve (AUC) during the IPGTT (c) and the IPITT (d). e The average concentration of the blood C-reactive protein (CRP) of the four groups. f The average concentration of the blood interleukin (IL)-6 in the four groups. Mean values of HFD, HFDOrl, and HFDPI statistically significant from ND (p < 0.05) denoted by *. Different letters denote the significance in the differences among HFD, HFDOrl, and HFDPI (p < 0.05)

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