Fig. 1

Effect of PAFE on NO production and cell viability in LPS-treated BV-2s. BV-2s were treated for 24 h with LPS after 30 min of processing various concentrations of PAFE. After then a production of nitrite and b cell viability were measured. BV-2s grown without treating PAFE and LPS-stimulation were considered control. c Expression of iNOS, COX-2, ERK, and p-ERK in BV-2s treated with PAFEs and treated with LPS. d Effect of PAFE on IL-6 secretion of BV-2s treated by LPS. PAFE of various concentrations was treated in BV-2s and treated by LPS for 24 h, and the secretion of IL-6 was then measured using ELISA. All data were presented together with ± S.D. as the average of the three independent experimental results. *p < 0.05 and **p < 0.01