Fig. 4

Effects of sesamolin on internal organs. A, B Spleen and liver weights. Mice were injected with 1 × 10⁵ or 1 × 10⁶ WEHI-3B cells and administered with vinblastine, sesamolin, or neither for 3 weeks (3 doses per week). Spleen (A) and liver (B) weights. Data are representative of experiments repeated at least three times with triplicate samples and are shown as mean ± SD. *P < 0.05 vs. leukemic mice (one-way ANOVA with Dunnett’s post-hoc tests). C Histopathological findings of fixed, embedded, and sectioned spleen tissues stained with H&E and evaluated by microscopy at 400× magnification. Data are representative of experiments repeated at least three times