Table 2 Information of ceramide biosynthesis genes
From: Enhanced ceramides production by Lactobacillus rhamnosus IDCC 3201 and its proposed mechanism
Gene | Precursor | Enzyme | PFAM domain |
|---|---|---|---|
degs | Dihydroceramide | Sphingolipid 4-desaturase | PF00487 (FA_desaturase) |
galc | Galactosylceramide | Galactosylceramidase | PF02057 (Glyco_hydro_59) |
gba | Glucosylceramide | Glucosylceramidase | PF02055 (Glyco_hydro_30) |
gba2 | Glucosylceramide | Non-lysosomal glucosylceramidase | PF12215 (Glyco_hydro_116N) |
sph | Sphingomyelin | Sphingomyelin phosphodiesterase | PF03372 (Exo_endo_phos) |
smpd1 | Sphingomyelin | Sphingomyelin phosphodiesterase | PF00149 (Metallophos) |
smpd2 | Sphingomyelin | Sphingomyelin phosphodiesterase | PF03372 (Exo_endo_phos) |
smpd3 | Sphingomyelin | Sphingomyelin phosphodiesterase | PF03372 (Exo_endo_phos) |
smpd4 | Sphingomyelin | Sphingomyelin phosphodiesterase | PF14724 (mit_SMPDase) |
enpp7 | Sphingomyelin | Sphingomyelin phosphodiesterase | PF01663 (Phosphodiest) |
cers1 | Sphingosine | Sphingoid base N-stearoyltransferase | PF03798 (TRAM_LAG1_CLN8) |
cers2 | Sphingosine | Very-long-chain ceramide synthase | PF03798 (TRAM_LAG1_CLN8) |
cers3 | Sphingosine | Very-long-chain ceramide synthase | PF03798 (TRAM_LAG1_CLN8) |