Table 3 The drug-like likeness profile of 10 chalcones was studied as NA inhibitors
Ligands | MW | log P | HBD | HBA | Rotatable bonds | Surface area |
|---|---|---|---|---|---|---|
1a | 242.249 | 3.4274 | 1 | 2 | 3 | 104.015 |
1b | 284.330 | 4.5090 | 0 | 2 | 5 | 123.429 |
1c | 312.365 | 4.0857 | 1 | 4 | 7 | 135.536 |
2a | 269.256 | 3.1965 | 1 | 4 | 4 | 114.502 |
2b | 310.368 | 5.0432 | 0 | 2 | 5 | 135.153 |
2c | 390.435 | 4.8845 | 1 | 5 | 8 | 169.342 |
3a | 268.268 | 2.9865 | 2 | 3 | 4 | 115.170 |
3b | 318.347 | 5.5141 | 0 | 2 | 5 | 139.391 |
3c | 360.409 | 4.8759 | 1 | 4 | 7 | 157.864 |
4b | 337.375 | 4.8123 | 0 | 4 | 6 | 145.641 |