Table 2 Summary of in vivo anti-gastritis of Cinnamomum cassia and its compounds
Author, Year Country | Animal (gender) (No. animal per group) | Gastritis (ulcer) induce methods | Intervention (pre-treatment) | Outcome measures | |||
|---|---|---|---|---|---|---|---|
Types and form of herb | Extraction method | Dose | |||||
Akira, 1986 [41] Japan | SD rat (male) (n = 10/4) | Cold-stress / Water immersion-stress-induced | Chinese cinnamon | Total plant extracts | Water | 50–100 mg/kg | Ulcer index gastric secretion |
Tanaka 1989 [42] Japan | SD rat (male) (n = 7–10/4) | Serotonin-induced | Cinnamomum cassia Blume, Lauracea | Total plant extracts | EtOH MeOH | 40 ~ 1000 μg/kg | Ulcer index gastric secretion |
Tankam 2013 [43] Japan | ddY mouse (male) (n = 10/4) | Immersion stress-induced / Ethanol-induced / HCl-induced / NSAIDs-induced | Cinnamomum cassia Blume(Lauraceae) | Total plant extracts | NA | 2, 10, 100 mg/g | Ulcer index |
In vitro and in vivo model | |||||||
 Jung 2011 [26] Korea | SD rat (male) (n = 6/4) | HCl/ethanol | Cinnamomi Ramulus, compounda | Total plant extracts, compounds | 70% EtOH | 50, 100 mg/kg | Gastric lesion evaluation |